Human growth hormone (HGH) and insulin-like growth factor 1 (IGF-1) are two important hormones involved in human growth and development. Though they are related, there are some key differences between them:
- HGH is a protein hormone secreted by the pituitary gland in the brain. It stimulates growth, cell reproduction and regeneration. HGH levels are highest during childhood and adolescence, when the most growth occurs. HGH production declines as we age. Supplementing with synthetic HGH aims to restore youthful levels and promote lean body mass.
- IGF-1 is a growth factor produced primarily by the liver, though it is also secreted locally by other tissues in the body. IGF-1 stimulates the growth of almost every cell in the body, especially skeletal muscle, cartilage, bone, liver, kidney, nerves, skin, hematopoietic cell, and lungs. It also plays a role in maintaining healthy blood vessels.
- HGH initiates the production of IGF-1. After HGH is released into the bloodstream, it activates receptors on the liver and other tissues, stimulating them to produce and release IGF-1. Therefore, IGF-1 levels generally reflect HGH levels.
- IGF-1 exerts growth-promoting effects on almost every cell in the body, while HGH targets specific cell types. Most of the growth-stimulating properties of HGH are actually mediated through IGF-1 production.
- The effects of IGF-1 are more long-lasting compared to HGH. IGF-1 remains active in the body for many hours, while the metabolic effects of HGH are more transient.
- HGH declines steadily with age, whereas IGF-1 levels remain fairly constant throughout adulthood but drop off more rapidly later in life.
- HGH is used as an injectable supplemental hormone, whereas IGF-1 cannot be directly administered. Attempting to increase IGF-1 requires stimulating natural production levels through lifestyle, nutrition, or enhancing the activity of HGH.
- Both HGH and IGF-1 have been studied for their anti-aging and athletic performance enhancing properties. However, HGH is more commonly used as a supplement, since directly supplementing IGF-1 can potentially lead to unwanted side effects like hypoglycemia, organ enlargement, and overgrowth of bone or tissue.
In summary, HGH is the primary stimulus for IGF-1 production. Most of the growth-promoting effects of HGH are actually mediated through the downstream production of IGF-1. While supplemental HGH aims to raise IGF-1 levels, directly administering IGF-1 can be problematic. Maintaining healthy natural production of both hormones is ideal for supporting muscle growth, body composition, bone density, and overall vitality.
If you are looking to increase your HGH and IGF-1 levels, be wary of synthetic injections that can upset your endocrine balance. I recommend exploring natural methods first, like adopting a HGH-boosting nutrition and fitness program. Compounds like amino acids, growth hormone secretagogues, and pituitary extracts may also provide a gentle nudge your body's natural production. Consult a knowledgeable practitioner to develop a safe, holistic hormone support protocol catered to your unique needs.
The physicians at Balance Hormone Center offer advanced hormone testing and personalized programs to help both men and women optimize hormone levels. I highly recommend speaking to their experts if you are seeking natural, efficacious ways to enhance youthful HGH and IGF-1 activity. Their cutting-edge therapies can restore vibrancy, health, and performance without disruptive side effects. Visit www.Balance Hormone Center.com today to schedule a consultation.
