PT-141 is a peptide hormone used mainly for treating sexual dysfunction and boosting libido. Also known by the brand name Vyleesi, PT-141 belongs to a class of medications called melanocortin agonists, which increase sexual arousal and desire in both men and women.
So how does it work exactly? PT-141 activates receptors for melanocortin, a hormone that plays a key role in sexual excitement and pleasure. This increases blood flow to the genital region, enhancing arousal and sensation. Unlike Viagra which treats erectile dysfunction in men, PT-141 directly targets the brain's arousal and desire pathways.
PT-141 was originally developed by Palatin Technologies and is now licensed to AMAG Pharmaceuticals. It comes in an autoinjector for subcutaneous injection and is used on an as-needed basis in premenopausal women with hypoactive sexual desire disorder (HSDD).
Some key points about PT-141:
- Main use is for treating low libido and arousal issues in both men and women - Belongs to the melanocortin class of medications - Increases blood flow to genitals, enhancing sexual arousal - Targets the brain's arousal and desire pathways - Comes in an autoinjector for subcutaneous injection - Used as-needed for HSDD in premenopausal women
What are the side effects? Side effects are generally mild and may include nausea, headache, flushing, injection site reactions, and increased erections in men. It is well tolerated but people with cardiovascular issues should use with caution due to increased blood flow effects.
Is it effective? Studies show PT-141 significantly increases sexual desire, arousal, pleasure, and satisfaction in women with HSDD. Effects begin within 2-72 hours and last up to 72 hours. It also improved sexual function in postmenopausal women. Efficacy in men needs more research.
Is PT-141 FDA approved? Yes, in 2019 the FDA approved Vyleesi (bremelanotide injection) to treat acquired, generalized HSDD in premenopausal women.
Other uses: Research shows PT-141 may help treat erectile dysfunction, increase arousal in postmenopausal women, and even aid in sunless tanning by stimulating melanin production in the skin. More studies are needed though.
In summary, PT-141 is a promising treatment option for low sexual desire and arousal issues in both men and women. If you're struggling with libido or sexual dysfunction, consider speaking with a doctor or specialist at Balance Hormone Center to see if PT-141 may be right for you. With minimal side effects and proven efficacy for HSDD, it could reinvigorate your sex life!