Premature ovarian failure (POF), also known as primary ovarian insufficiency (POI), is a condition characterized by loss of normal ovarian function before the age of 40. This results in premature menopause and infertility. POF affects approximately 1% of women under the age of 40.
What causes POF? There are several potential causes:
- Genetic factors - women with family history of POF are at higher risk - Autoimmune disease - 20-30% cases are due to the immune system attacking the ovaries - Radiation/chemotherapy - cancer treatments can damage ovaries
- Chromosomal abnormalities - Turner's syndrome, Fragile X syndrome
- Infections - mumps, tuberculosis, malaria
What are the symptoms of POF? The main symptoms are:
- Irregular periods or amenorrhea (absence of periods) - Hot flashes, night sweats - signs of estrogen deficiency - Vaginal dryness - Difficulty conceiving
Other symptoms like mood swings, decreased sex drive, and sleep disturbances may occur due to hormone changes.
How is POF diagnosed? Diagnosis is based on:
- Abnormal follicle stimulating hormone (FSH) level - FSH will be elevated - Low estradiol levels - Absence of ovulation
Pelvic ultrasound or other tests may be done to rule out other causes.
What is the treatment for POF? There is no cure, but treatment focuses on managing symptoms. Options include:
- Hormone replacement therapy (HRT) with estrogen/progesterone to relieve menopausal symptoms - Oral contraceptive pills for younger women to regulate cycles - Fertility drugs/IVF may be tried to improve fertility
At Balance Hormone Center, we provide comprehensive hormone replacement and optimization services to help women experiencing POF and early menopause. Our highly trained physicians will evaluate your hormone levels and design a personalized treatment plan using bioidentical hormones to relieve your symptoms.
With therapies including estrogen creams, testosterone pellets, DHEA supplements, and more, we can help you find balance again. We also offer fertility consults, nutrition advice and mental health support. Let Balance Hormone Center get your hormones and health back on track. Schedule a consult today to start your journey!